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[Answered]: A nurse is caring for older clients in an acute…

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A nurse is caring for older clients in an acute care facility. The clients are receiving various medications as part of their treatment plan. When administering the medications to these clients, the nurse integrates information about changes in pharmacokinetics in this client population, identifying which factor as most important? Decreased renal and liver function contributes to an increased half-life for many drugs Changes in gastrointestinal (GI) motility increase the absorption time for many drugs Preexisting chronic conditions complicate the drugs’ distribution and metabolism Drug distribution is unpredictable due to metabolic and body-composition factors

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