[Expert Solution]: A 70-year-old woman comes for a routine…

A 70-year-old woman comes for a routine annual physical exam. She reports that she feels well and exercises daily. She has a history of hypertension managed with lisinopril and amlodipine. She monitors her blood pressure at home; it ranges from 110/60 to 125/75 mm HG. Additional medications include aspirin 81 mg daily, calcium and vitamin D supplements and monthly alendronate to prevent osteoporosis. The patient is 5 ft 3 in tall and weight 150 lb; BMI is 26.6 kg/m2. Heart rate is 75/min, respirations are 10/min, and blood pressure is 135/80 mm HG. Jugular venous pressure is 6 cm H2O. Carotid artery upstrokes are normal; there is a faint bruit on the left. Lungs are clear to auscultation. Cardiac exam discloses a single S1 and a physiologically split S2; there are no murmurs. There are no abdominal bruits. Posterior tibialis and dorsalis pedis pulses are 2+. Laboratory studies show the following: Blood • Cholesterol, total 210 mg/dL • HDL 44 mg/dL • LDL 120 mg/dL • Triglycerides 210 mg/dL Carotid artery ultrasonography shows stenosis of 65% on the left and less than 49% on the right. Which of the following is the most appropriate pharmacologic intervention? Rosuvastatin Clopidogrel Alirocumab Dipyridamole