[Solved]: While performing a medication review for a…

While performing a medication review for a 75-year-old woman, which of the following would be most concerning due to possible drug-drug interaction? Metformin for type 2 diabetes mellitus and doxycycline for rosacea Fosfomycin for UTI and simvastatin for hypercholesterolemia Low-dose aspirin for secondary CV prevention and lubiprostone for chronic constipation Chlorothiazide for hypertension and sertraline for depression