CASE STUDY: Ms. Lewis, a 24-year-old woman is experiencing shortness of breath and loss of appetite. Physical exam reveals an S3 heart sound, crackles in the lungs, hypoxia, elevated blood pressure (180/100) and edema. She recently experienced an acute muscle injury. She reports self-medicating with 8 Ibprofen tablets per day for pain for 14 days. Clinical labs reveal acidosis, elevated potassium, white blood cell count of 6 X 103 per milliliter, hematocrit of 33%, blood urea nitrogen level of 36 mg per dL, and a creatinine level of 2.5 mg/dL, with a creatinine clearance of 70 mL. 1. Investigate how muscle injury can lead to kidney damage. Again be sure to describe the mechanism and the outcome.
[Answered]: CASE STUDY: Ms
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